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Prevalence of vitamin D deficiency in girls with idiopathic central precocious puberty

Yue Zhao, Wenjun Long, Caiqi Du, Huanhuan Yang, Shimin Wu, Qin Ning, Xiaoping Luo

Frontiers of Medicine 2018, Volume 12, Issue 2,   Pages 174-181 doi: 10.1007/s11684-017-0544-5

Abstract:

The relationship between vitamin D deficiency and idiopathic central precocious puberty (ICPP) hasThe ICPP group had significantly lower serum 25-hydroxyvitamin D (25[OH]D) levels than the control groupserum 25[OH]D was found at 31.8 ng/ml for ICPP with and without adjusting the different confoundingCorrelation analysis showed that vitamin D level is correlated with BMI and some metabolic parametersOur study suggested that vitamin D status may be associated with ICPP risk and may have a threshold effect

Keywords： idiopathic central precocious puberty     threshold effects     vitamin D status    

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Identification of transporter proteins for PQQ-secretion pathways by transcriptomics and proteomics analysis in

Hui Wan,Yu Xia,Jianghua Li,Zhen Kang,Jingwen Zhou

Frontiers of Chemical Science and Engineering 2017, Volume 11, Issue 1,   Pages 72-88 doi: 10.1007/s11705-016-1580-4

Abstract: dehydrogenases play key roles in the oxidation of important substrates for the biotechnology industry, such as vitamin

Keywords： 2D-DIGE     pqqB     pyrroloquinoline quinone     RNA-Seq     Vitamin C    

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An Eight-Step Continuous-Flow Total Synthesis of Vitamin B1 Article

Meifen Jiang, Minjie Liu, Weijian Li, Yingqi Xia, Fener Chen

Engineering 2024, Volume 32, Issue 1,   Pages 230-239 doi: 10.1016/j.eng.2023.01.016

Abstract:

Vitamin B1 is widely applied in the healthcare and food industry as an antineuritic andThis study reports on an integrated eight-step continuous-flow synthesis of vitamin B1 fromVitamin B1 was produced with a separated yield of 47.7% and high purity, with a total residence

Keywords： Vitamin B1     Continuous-flow synthesis     Micro-reactor     Continuous manufacturing    

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Current status and prospects of reliability systems engineering in China

Frontiers of Engineering Management 2021, Volume 8, Issue 4,   Pages 492-502 doi: 10.1007/s42524-021-0172-2

Abstract: This study provides a systematic overview of the advent and evolution of reliability systems engineering (RSE) in China, and the latest RSE development, that is, model-based RSE (MBRSE), is emphatically introduced. The establishment of the system architecture and conceptual models of MBRSE is first described. The fundamental theory and methodology of MBRSE are then elaborated, with a V-model as the core of this approach. The development of various MBRSE platforms and the effectiveness of their implementation over the past 30 years are presented. The prospective trends in the development of RSE in China are outlined.

Keywords： reliability     effectiveness     model-based systems engineering     reliability systems engineering    

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Present status and progress of neoadjuvant chemoradiotherapy for esophageal cancer

Jing Liu, Jinbo Yue, Ligang Xing, Jinming Yu

Frontiers of Medicine 2013, Volume 7, Issue 2,   Pages 172-179 doi: 10.1007/s11684-013-0268-0

Abstract:

Trimodality based on neoadjuvant chemoradiotherapy (nCRT) followed by surgery is gaining popularity as a treatment strategy for locally advanced esophageal cancer. In this review, we summarize the role of nCRT and the recommended nCRT regimens based on clinical trials and meta-analyses. We analyze the relationship of nCRT with pathologic complete response (pCR) and then identify potential predictive markers of response. Compared with surgery alone and neoadjuvant chemotherapy followed by surgery, trimodality provides longer survival and has the advantage of local control compared with definitive chemoradiotherapy. The standard regimen is a platinum-based regimen with a radiation dose range of 41.4–50.4βGy by conventional fractionation. Evidence shows that patients with pCR tend to live longer than non-responders, indicating that pCR is a significant prognostic factor for patients with esophageal cancer. Individualized medicine requires predictive markers of individual patients based on their own genes. Currently, no definite marker is proved to be sufficiently sensitive and specific for use in clinical practice, although 18-fluorodeoxyglucose positron emission tomography shows promise in predicting response to nCRT.

Keywords： esophageal cancer     neoadjuvant     chemoradiotherapy    

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Evaluation of the ecological status with benthic indices in the coastal system: the case of Bohai Bay

Wenqian CAI,Wei MENG,Lusan LIU,Kuixuan LIN

Frontiers of Environmental Science & Engineering 2014, Volume 8, Issue 5,   Pages 737-746 doi: 10.1007/s11783-013-0617-x

Abstract: Index (AMBI), Shannon–Wiener Index and -statistic) were applied together to evaluate the ecological statusThe results showed a clear spatial gradient from a worse ecological status in the near-shore areas (especiallyaround Haihe and Jiyun River Estuaries) to a better status in the offshore areas.Furthermore, there is indication that the ecological status is related to excess input of wastewaterIn a word, AMBI, Shannon–Wiener Index and -statistic could be able to assess the benthic ecological status

Keywords： AZTI’s Marine Biotic Index     Shannon-Wiener Index     W-statistic     ecological status     coastal system     Bohai    

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EGG PRODUCTION IN CHINA: CURRENT STATUS AND OUTLOOK

Frontiers of Agricultural Science and Engineering 2021, Volume 8, Issue 1,   Pages 25-34

Abstract:

• China is now the largest egg production country worldwide

• Egg production in China is characterized by diversity in several aspects

• China is now capable of breeding new varieties, with more than 50% of the market share

• Policies have been implemented to ensure sustainable development of egg production

• Integrating crop-chicken-vegetable production system is established

 

Eggs are one of the most nutritious and affordable animal products worldwide. From 1985, egg production in China has retained the leading place in the world. A total of 33 Mt of eggs were produced in 2019 representing ˃ 40% of the world total production. Egg production in China is characterized by diversity in several aspects, including layer breeds, products and production systems. New breeds and synthetic lines are developed to improve the genetic potentials of egg production and feed efficiency of layers. In the past, layer farms were run mostly by small households with 100 to 1000 layers per farm. Over the past decades, egg production in China has developed toward standardization and expansion of production systems, and many of these modern intensive farms raise millions of layers. Although the Chinese egg products maintain strong competitiveness over other animal products and imported egg products, the egg industry will grow at a slower pace compared to the past. Chinese consumers are more concerned about the quality and safety of eggs and egg products, as well as the environmental issues related to animal production, which presents challenges for the Chinese egg industry.

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HIGH-PERFORMANCE COMPUTATION AND ARTIFICIAL INTELLIGENCE IN PESTICIDE DISCOVERY: STATUS AND OUTLOOK

Frontiers of Agricultural Science and Engineering 2022, Volume 9, Issue 1,   Pages 150-154 doi: 10.15302/J-FASE-2021419

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Catalytic conversion of biomass-derived compounds to various amino acids: status and perspectives

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 7,   Pages 817-829 doi: 10.1007/s11705-022-2254-z

Abstract: Amino acids are important nitrogen-containing chemicals that have a variety of applications. Currently, fermentation is the widely employed method to produce amino acids; however, the products are mostly limited to natural amino acids in the L-configuration. Catalytic synthesis is an alternative approach for the synthesis of amino acids with different types and configurations, where the use of renewable biomass-based feedstocks is highly attractive. To date, several lignocellulose and triacylglycerol-derived intermediates, typically α-keto acids and α-hydroxyl acids, have been transformed into amino acids via the amination reaction in the presence of additional nitrogen sources (i.e., NH3·H2O). Making full use of inherent nitrogen in biomass (i.e., chitin and protein) to produce amino acids avoids the use of extra nitrogen sources and meets the requirements of green chemistry, which is attracting increasing attention. In this review, we summarize different chemical-catalytic systems for the transformation of biomass to amino acids. An outlook on the challenges and opportunities for more effective production of amino acids from biomass by catalytic methods is provided.

Keywords： biomass     amino acids     chitin     nitrogen-containing compounds     lignocellulose    

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THE ANTHOCYANIN BIOSYNTHETIC REGULATOR MDMYB1 POSITIVELY REGULATES ASCORBIC ACID BIOSYNTHESIS IN APPLE

Jianping AN, Xiaofei WANG, Chunxiang YOU, Yujin HAO

Frontiers of Agricultural Science and Engineering   Pages 231-235 doi: 10.15302/J-FASE-2020367

Abstract: Ascorbic acid (AsA, vitamin C) is involved in the regulation of many aspects of plant growth and development

Keywords： anthocyanin     apples     ascorbic acid     MdMYB1     vitamin C    

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EGG PRODUCTION IN CHINA: CURRENT STATUS AND OUTLOOK

Ning YANG

Frontiers of Agricultural Science and Engineering 2021, Volume 8, Issue 1,   Pages 25-34 doi: 10.15302/J-FASE-2020363

Abstract: Eggs are one of the most nutritious and affordable animal products worldwide. From 1985, egg production in China has retained the leading place in the world. A total of 33 Mt of eggs were produced in 2019 representing ˃ 40% of the world total production. Egg production in China is characterized by diversity in several aspects, including layer breeds, products and production systems. New breeds and synthetic lines are developed to improve the genetic potentials of egg production and feed efficiency of layers. In the past, layer farms were run mostly by small households with 100 to 1000 layers per farm. Over the past decades, egg production in China has developed toward standardization and expansion of production systems, and many of these modern intensive farms raise millions of layers. Although the Chinese egg products maintain strong competitiveness over other animal products and imported egg products, the egg industry will grow at a slower pace compared to the past. Chinese consumers are more concerned about the quality and safety of eggs and egg products, as well as the environmental issues related to animal production, which presents challenges for the Chinese egg industry.

Keywords： poultry farms     China     diversity     egg production     trends    

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Advancing ion-exchange membranes to ion-selective membranes: principles, status, and opportunities

Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 2, doi: 10.1007/s11783-023-1625-0

Abstract:

● IEM ion/ion selectivities of charge, valence, & specific ion are critically assessed.

Keywords： Ion-exchange membranes     Selectivity     Separations    

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Arsenic in the treatment of newly diagnosed acute promyelocytic leukemia: current status and future research

Jiong HU

Frontiers of Medicine 2011, Volume 5, Issue 1,   Pages 45-52 doi: 10.1007/s11684-011-0117-y

Abstract:

Acute promyelocytic leukemia (APL) is a subtype of acute myeloid leukemia. In past decades, intensive studies on the biology and treatment of this disease have resulted in a remarkably thorough understanding of its pathogenesis and improvement of treatment outcomes. In particular, the introduction of all-trans retinoic acid to conventional chemotherapy improved dramatically the remission and survival rates of APL patients and consequently became the major treatment modality for it. In the last decade, the groundbreaking development of arsenic further improved the survival rate of APL patients. As the most active agent in APL, arsenic directly degrades the PML-RARα fusion transcript, leading to the differentiation and apoptosis of leukemia cells and the potential eradication of APL leukemia-initiating cells (LICs), thus making the disease a potentially curable type of leukemia. More notably, the recent development of oral arsenic compounds may further enhance not only clinical outcomes but also the convenience of patients, which may dramatically change the APL clinical scenario in the near future.

Keywords： acute promyelocytic leukemia     arsenic     all-trans retinoic acid     survival    

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Development of Bioimplants with 2D, 3D, and 4D Additive Manufacturing Materials Review

Guo Liu, Yunhu He, Pengchao Liu, Zhou Chen, Xuliang Chen, Lei Wan, Ying Li, Jian Lu

Engineering 2020, Volume 6, Issue 11,   Pages 1232-1243 doi: 10.1016/j.eng.2020.04.015

Abstract: However, 3D printable materials are still quite limited for the fabrication of bioimplants.In this work, 2D/3D AM materials for bioimplants are reviewed.complex and dynamic biological structures in the human body based on 4D printing hybrid ceramic precursorprinting technology, the development of bioimplants and soft/rigid hybrid biological structures with 2D/3D/4D AM materials can be anticipated.

Keywords： Bioprinting     2D additive manufacturing     3D printing     4D printing     Bioimplants    

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Energy and environment in Chinese rural housing: Current status and future perspective

Xudong YANG, Yi JIANG, Ming YANG, Ming SHAN,

Frontiers in Energy 2010, Volume 4, Issue 1,   Pages 35-46 doi: 10.1007/s11708-010-0001-5

Abstract: Possible causes are analyzed, the current status explained and possible development trends predicted.

Keywords： rural energy     energy-saving     sustainability    

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Title Author Date Type Operation

Prevalence of vitamin D deficiency in girls with idiopathic central precocious puberty

Yue Zhao, Wenjun Long, Caiqi Du, Huanhuan Yang, Shimin Wu, Qin Ning, Xiaoping Luo

Journal Article

Identification of transporter proteins for PQQ-secretion pathways by transcriptomics and proteomics analysis in

Hui Wan,Yu Xia,Jianghua Li,Zhen Kang,Jingwen Zhou

Journal Article

An Eight-Step Continuous-Flow Total Synthesis of Vitamin B1

Meifen Jiang, Minjie Liu, Weijian Li, Yingqi Xia, Fener Chen

Journal Article

Current status and prospects of reliability systems engineering in China

Journal Article

Present status and progress of neoadjuvant chemoradiotherapy for esophageal cancer

Jing Liu, Jinbo Yue, Ligang Xing, Jinming Yu

Journal Article

Evaluation of the ecological status with benthic indices in the coastal system: the case of Bohai Bay

Wenqian CAI,Wei MENG,Lusan LIU,Kuixuan LIN

Journal Article

EGG PRODUCTION IN CHINA: CURRENT STATUS AND OUTLOOK

Journal Article

HIGH-PERFORMANCE COMPUTATION AND ARTIFICIAL INTELLIGENCE IN PESTICIDE DISCOVERY: STATUS AND OUTLOOK

Journal Article

Catalytic conversion of biomass-derived compounds to various amino acids: status and perspectives

Journal Article

THE ANTHOCYANIN BIOSYNTHETIC REGULATOR MDMYB1 POSITIVELY REGULATES ASCORBIC ACID BIOSYNTHESIS IN APPLE

Jianping AN, Xiaofei WANG, Chunxiang YOU, Yujin HAO

Journal Article

EGG PRODUCTION IN CHINA: CURRENT STATUS AND OUTLOOK

Ning YANG

Journal Article

Advancing ion-exchange membranes to ion-selective membranes: principles, status, and opportunities

Journal Article

Arsenic in the treatment of newly diagnosed acute promyelocytic leukemia: current status and future research

Jiong HU

Journal Article

Development of Bioimplants with 2D, 3D, and 4D Additive Manufacturing Materials

Guo Liu, Yunhu He, Pengchao Liu, Zhou Chen, Xuliang Chen, Lei Wan, Ying Li, Jian Lu

Journal Article

Energy and environment in Chinese rural housing: Current status and future perspective

Xudong YANG, Yi JIANG, Ming YANG, Ming SHAN,

Journal Article